New Disinfectant QASc
We have prepared completely new quaternary ammonium salts - substances with a broad-spectrum effect.
We have prepared completely new quaternary ammonium salts - substances with a broad-spectrum effect.
Currently, the incidence of bacteria resistance to antimicrobial agents such as antibiotics, but also commonly used disinfectants, becomes an issue in the field of disinfection. In many cases, multidrug-resistant strains to both groups of anti-infectives compounds were described. This trend results from the long-term use of antibiotics and disinfectants, especially in hospitals where bacteria are constantly exposed to the selection pressure of antibiotics and thus the bacteria are able to develop resistance to antimicrobials due to evolutionary mechanism.
We have prepared completely new substances with a broad spectrum effect: high antimicrobial potential against bacteria (EN 13727 + A2), mycobacteria (EN 14348), fungi (EN 13624) and enveloped viruses (EN 14476 + A2). Substance is significantly effective even at very low concentration.
Advantages
Effective at low concentration (0,06%):
• low production costs
• low allergy potential
• friendly to surfaces
• waste-water friendly
Potential Applications
• healthcare
• agriculture
• food industry
Czech patent 309377 granted; some compounds structures are not published - kept confidential. Technology is owned by University Hospital Hradec Králové. Compounds were tested and certified according to EN standards. The development was supported by the Technology Agency of the Czech Republic within the programme for applied research, experimental development and Innovation GAMA 2 – Project TP01010034 – Centre for Transfer of Biomedical Technologies – PoC2.
Researcher at Biomedical Research Center UH HK
Nominee for a Prize of the Mayor of Hradce Králové for research activities & Awarded by the Medal of Hradce Králové for research activities
Author & coauthor of 40+ scientific publications with IF
Coauthor of 2 book chapters & H-index: 14 &
Citation without self citation: 349
Research focus on Quaternary ammonium compounds, radioprotective compounds and acetylcholinesterase reactivators
Head of Biomedical Research Center UH HK
Nominee for a Prize of the Mayor of Hradce Králové for research activities & Awarded by the Medal of Hradce Králové for research activities
Author & coauthor of 150+ scientific publications with IF
Coauthor of 8 book chapters & editor of 1 monograph on Alzheimer's disease & editor of Special Issue with IF 3
6 patents granted, 1 licensed, 3 utility models granted
For more detailed information, do not hesitate to contact us directly:
Lucie Bartošová, Ph.D., lucie.bartosova@fnhk.cz or +420 495 832 925.
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