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Brain Phantom

Brain Phantom for ultrasound navigated brain surgery training.

A very promising way to control the course of brain tumor surgery is through a combination of several imaging methods. The "underlying three-dimensional detailed maps" of the whole brain are composed in advance of magnetic resonance imaging and computed tomography. During and before the operation, some parts of the brain move, and these "maps" are then slightly - but significantly - inaccurate. Therefore, just before the procedure and during the work of the neurosurgeon, real-time ultrasound control helps to show the current exact situation of tumor removal, movement of parts of the brain, etc. on previously obtained "maps" - thus serving as a surgeon's navigation. This procedure is not easy to handle and usable and meaningful options, how the surgeon can build a skill, gain experience is not for many reasons enough. There is no available and practically usable training model on the market for acquiring all the necessary skills in a way close to the actual operation.

Descricption of the Invention
Operable brain model (phantom) contains key brain structures and includes several tumors. Compared to available solutions (expensive silicone models - useful for practicing imaging, not surgical procedures, or virtual models - good for basic orientation but rather unreal to "manual" work training), a way to produce a relatively inexpensive disposable phantom that is truly "consumed" in an exercise which, with its texture and other physical properties, truly simulates individual parts of the brain and the imaging methods used to depict it very closely, as real parts of the brain.

The system includes a method of manufacturing individual parts, a method of assembling the entire brain phantom with great precision, a method of manufacturing materials for individual brain parts, recipes for the production of materials ensuring fidelity to the original, protection during transport and longer and easier storage.

Commercial Use
Due to the rise of perioperative guided ultrasound technology, which is being promoted by companies like Brainlab AG and BK Medical (R), sophisticated phantoms are already in great demand for training in this technology. The presentation of this "hands-on" technology is impossible without a quality phantom. Such a phantom should be used in areas ranging from R+D, marketing, presentation at congresses, holding hands-on workshops, for direct sales to neurosurgical workplaces and individuals. There is currently no such phantom on the market.

According to the World Federation of Neurosurgery, which lists the numbers of surgeons in most countries of the world, it can be estimated: ca. 15,000 potential users in the "developed world" specializing in head neurosurgery. We potentially consider more than a multiple in the future for early training at medical faculties and before attestation training.

Intended for target users - physicians, manufacturers of medical equipment to demonstrate the function and organize workshops for physicians - users.  

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Technology is owned by University Hospital Hradec Králové and is protected with know-how (recipe, production process, construction of production molds, data bases and modified 3D brain data models). The development of molds and materials is going through the last phases of the Proof of Concept. This will be followed by practical development for mass production and tuning of processes, mold life, monitoring of deviations and testing of storage and consumption conditions. At that moment, we will intensively look for a smart money investor / business angel / CEO to establish a start-up. The development was supported by the Technology Agency of the Czech Republic within the programme for applied research, experimental development and Innovation GAMA 2Project TP01010034 – Centre for Transfer of Biomedical Technologies – PoC2.

Team of Inventors

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MUDr. Michael Bartoš
University Hospital Hradec Králové

Department of Neurosurgery

Principal investigator & coinvestigator of multiple research projects and clinical studies

Specializes in cranial neurosurgery and has gained extensive experience in navigated ultrasound in glioma surgery since 2013

Contact Us

For more detailed information, do not hesitate to contact us directly:
Lucie Bartošová, Ph.D., or +420 495 832 925.

Stay in touch with us on social media where you can follow recent progress in developing technologies.

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